急性冠脉综合征患者组织因子动态检测

Chinese Journal of Thrombosis and Hemostasis(2012)

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Abstract
目的动态观察血浆组织因子(TF)在急性冠脉综合征(ACS)患者急性期及恢复期的表达。方法采用ELISA方法检测39例ACS患者[急性心肌梗死(AMI)26例,不稳定型心绞痛(UA)13例]急性期和25例患者(15例AMI,10例UA)恢复期的血浆TF抗原;以同期61例健康体检者作为对照。结果与健康对照组比较,血浆TF(ng/L)AMI组:251.14±106.73,UA组246.60±104.45,对照组197.18±94.91,(P<0.05);恢复期AMI患者血浆TF水平为221.70±99.23,UA为201.50±118.24,较急性期均呈下降趋势,虽仍高于对照组,但无统计学意义(P>0.05)。结论动态观察ACS患者TF表达对冠状动脉血栓性事件的防治具有重要的临床意义。
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Key words
Acute,Tissue factor,Coronary syndrome
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