Atomic insight into short helical peptide comprised of consecutive multiple aromatic residues
Chemical Communications(2022)
摘要
The occurrence of sequential multiple aromatic residues in a helical sequence is rare compared to the β-sheet rich structure. Here, using helix promoting α-aminoisobutyric acid (Aib) residues, we unravel atomistic details of the helical secondary structure formation and the super helical assembly of two heptapeptides composed of sequential five and six phenylalanine (Phe) residues.
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关键词
short helical peptide,consecutive multiple aromatic residues
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