Asymmetric synthesis of cis-aminochromanol

Karl B Hansen,Philippe Rabbat,Shawn A Springfield,Paul N Devine,Edward J.J Grabowski,Paul J Reider

Tetrahedron Letters（2001）

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摘要

An efficient asymmetric synthesis of cis-aminochromanol was achieved in seven steps. The absolute stereochemistry of cis-aminochromanol was derived from (salen)Co(III)-catalyzed phenol opening of methyl glycidate.

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asymmetric synthesis

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