Review: Anti-infectives Advances in tetracycline antibiotics

The patent status of tetracycline research for the period of 1991 to 1995 is presented. Topics covered include new tetracyclines with intrinsic antibacterial activity against tetracycline-resistant bacteria or which potentiate the activity of the older tetracyclines, new natural products, new chemical methods, and non-infectious disease uses for tetracyclines.