Multiple Primary Malignancies: "Non-Codified" Associations

A retrospective analysis of the most important international statistics on non-hereditary multiple tumors has demonstrated neoplastic associations (of unknown pathology) in which the appearance of a neoplasm in a determinate organ increases the risk of developing a second tumor in a “predefined” organ. Here we examine the most frequent associations, starting from an “index tumor” arising in a particular organ, and analyze the site and type of second and third tumors. The goal is to identify potential new syndromes as yet referred to as “not codified. ” Since colorectal tumors are dealt with in a separate chapter, only those neoplasms frequently observed by the department of General Surgery are considered in the following.