Effects of diphosphonate on primary osteoporosis pain by intravenous.

Objective To assess the management of primary osteoporosis pain using diphosphonate intravenously.Methods 68 patients with primary osteoporosis pain were divided into three groups by the loss conditions of bone mineral density(commonly use T to express),according to T score and age,the incadronate disodium was injected.All the groups were given calcium orally during the treatment.The visual analogy scales(VAS)were measured,and the bone mineral density were examined by DEXA before and after treatment.Results The pain intensity significantly decreased after the treatment without apparent adverse effects(P0.05),T score of bone mineral density slightly increased after treatment(P0.05).Conclusion The results suggest that it is convenient,adherence,safe,quick and effective on the management of primary osteoporosis pain by diphosphonate intravenous.