Convergent, parallel synthesis of a series of β-substituted 1,2,4-oxadiazole butanoic acids as potent and selective αvβ3 receptor antagonists

Bioorganic & Medicinal Chemistry Letters(2006)

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Abstract
Synthesis of a series of potent and selective αvβ3 antagonists containing a 1,2,4-oxadiazole core is reported.
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Key words
Integrin,Vitronectin,αvβ3,Antagonist,1,2,4-Oxadiazole,RGD,Peptidomimetic
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