慢性阻塞性肺病对脂蛋白(a)水平的影响

Journal of Xianning College(Medical Sciences)(2006)

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Abstract
目的观察慢性阻塞性肺疾病(COPD)患者脂蛋白(a)[Lp(a)]水平是否同COPD合并冠心病的高发生率相关。方法检测90名COPD患者及与之年龄、性别、吸烟史等相近的90例健康人的血脂水平。结果同健康对照组相比,COPD患者的Lp(a)及载脂蛋白B-100(ApoB100)水平显著下降,且两者水平呈明显相关性,治疗用药及是否吸烟对ApoB100影响不大。结论COPD患者易患冠心病的原因与Lp(a)的高低关系不确切,而与患者血液粘稠度升高相关。
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Key words
Apolipoprotein B-100,Lipoprotein(a),Chronic obstructive pulmonary disease
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