Severity Of Group B Streptococcal Arthritis In Selected Strains Of Laboratory Mice

M Puliti, F Bistoni,C von Hunolstein,G Orefici,L Tissi

INFECTION AND IMMUNITY（2001）

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摘要

The susceptibilities of C3H/HeN, BALB/c, and C57BL/6N mouse strains to group B streptococci (GBS) infection were evaluated. C3H/HeN mice developed severe polyarthitis; mild lesions and no lesions were observed in BALB/c and C57BL/6N mice, respectively, a correlation between the severity of arthritis, the number of GBS in the joints, and local interleukin-6 and interleukin-1 beta production was evident.

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interleukin 1,interleukin 6

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