Hepatic drug conjugation/deconjugation systems in hepatosplenic schistosomiasis
BIOCHEMICAL PHARMACOLOGY（1990）
Abstract
The biotransformation capacity of the liver is altered in hepatosplenic schistosomiasis being more in favor of deconjugation pathways. These alterations should be considered when xenobiotics are administered and in studies of hepatic toxicity and carcinogenicity.
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Key words
pathology,drug metabolism,helminths
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