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无抽搐电休克对难治性抑郁症患者多导睡眠图的影响

Journal of Neurology and Neurorehabilitation(2012)

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Abstract
目的探讨无抽搐电休克(MECT)疗法对难治性抑郁症(TRD)患者多导睡眠图(PSG)的影响。方法应用PSG仪监测30例TRD患者在MECT治疗前和治疗14次后PSG的变化,并与30名正常对照者进行比较。结果与正常对照者相比,TRD患者的睡眠总时间(TST)减少、睡眠潜伏期(SL)延迟、觉醒时间(AT)增加、快眼动睡眠时间(RT)增多、快眼动睡眠潜伏期(RL)缩短、S1和S2增加以及慢波睡眠(SWS)减少。TRD患者在MECT治疗后,出现TST增加、SL缩短、AT减少、RT减少及SWS增加,但RL无明显变化。结论 TRD患者的PSG指标在MECT治疗后有所改善。
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Key words
treatment-resistant depression,polysomnography,modified electroconvulsive therapy
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