Myocardial function in hearts with transgenic overexpression of the G protein-coupled receptor kinase 5.
The Annals of Thoracic Surgery(2001)
Abstract
Background. Chronic heart failure is associated with impairment of the myocardial β-adrenergic receptor (β-AR) system. In this study, the effects of G protein–coupled receptor kinase 5 (GRK5) overexpression on myocardial performance were directly assessed in the hearts of transgenic mice using an isolated work-performing murine heart preparation and computerized analysis of functional data.
MoreTranslated text
Key words
cardiac output,control group,stroke volume,transgenic mice,g protein coupled receptor,cardiac function,adrenergic receptor
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined