THE FACILE SYNTHESIS OF 1-AMINOPHOSPHONATES FROM 1-NITROPHOSPHONATE PRECURSORS
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS(2006)
Abstract
1-Aminophosphonates may be generated in high yield and spectroscopic purity by the treatment of 1-nitrophosphonates with LiBH4/Me(3)SiCl in THF at room temperature.
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Key words
1-nitrophosphonates,1-aminophosphonates,thrombin,thrombin inhibition
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