Decrease of synovial power Doppler flow in arthritis patients under therapy with the TNF-alpha inhibitor adalimumab

Objectives: Power Doppler ultrasound (PDUS) is used to verify the efficacy of a current treatment strategy. Changes of synovial perfusion in arthritic joints are evaluated using quantitative three-dimensional (3D) power Doppler analyses (voxel count) under anti-inflammatory treatment with adalimumab in arthritis patients.