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医药中间体茄尼醇的体外抗菌活性研究

Qilu Pharmaceutical Affairs(2007)

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Abstract
目的研究从废弃的烟草叶中提取纯化后的医药中间体茄尼醇,对革兰阴性和革兰阳性菌的体外抗菌活性。方法采用琼脂扩散法和两倍稀释法考察茄尼醇对多种标准菌株和临床分离菌株的抗菌活性。结果与结论茄尼醇对被测菌株中的革兰阴性菌(大肠埃希氏菌和铜绿假单胞菌)和革兰阳性菌(金黄色葡萄球菌和草分枝杆菌)具有显著的抗菌活性,而对枯草杆菌和环状芽孢杆菌活性较弱。
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Key words
Solanesol,antibacterial activity,tobacco leaves(Nicotiana tabacum L)
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