Some Guidelines For Defining Personality Differences In Rats
HANDBOOK OF BEHAVIOR GENETICS(2010)
Abstract
Whereas many behavioral studies with rats have been traditionally concerned with tests and/or models attempting to deal with
subjects such as anxiety, depression, hyperactivity, alcoholism and drug abuse, as they pertain to the human conditions, critical
and integrated analyses of the vast amounts of information which have been accumulated, and an application of the same to
the realm of personality traits, are long overdue. One such application, for example, might deal with the etiology of substance
use and abuse toward which different animal models, considered together, can undoubtedly play a decisive role, especially
as genetic factors are known to be extensively involved in the temperament differences underlying these phenomena in both
rats and humans. The major contributions of such models toward this goal will, of course, pertain to unraveling the fundamental
neurochemical processes involved and to deciphering their genetic origins.
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