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Azepanone-Based Inhibitors of Human Cathepsin S: Optimization of Selectivity Via the P2 Substituent

Jeffrey K. Kerns,Hong Nie,William Bondinell,Katherine L. Widdowson,Dennis S. Yamashita,Attiq Rahman,Patricia L. Podolin,Donald C. Carpenter,Qi Jin,Benoit Riflade,Xiaoyang Dong,Neysa Nevins,Paul M. Keller,Laura Mitchell,Thaddeus Tomaszek

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2011）

引用 12|浏览49
关键词
Cathepsin S,Cathepsin K,Cathepsin L,Azepanone,1-Methylcyclohexyl alanine,Cysteine protease
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