Chrome Extension
WeChat Mini Program
Use on ChatGLM
VIPCreated with Sketch.

3-Cyano-6-(5-methyl-3-pyrazoloamino)pyridines: Selective Aurora A kinase inhibitors

Ryoichi Ando,Hiroshi Ikegami,Makoto Sakiyama,Shinsuke Ooike,Masayuki Hayashi,Yasuhiro Fujino,Daisuke Abe,Hideo Nakamura,Tadashi Mishina,Harutoshi Kato,Yumiko Iwase,Hideo Tomozane,Masahiko Morioka

Bioorganic & Medicinal Chemistry Letters（2010）

Cited 29|Views9
No score
Abstract
Compound 6 exhibited a potent Aurora A kinase inhibitory activity (Ki=1.2nM) and was effective in antitumor mice model at a dose of 30mg/kg po qd.
More
Translated text
Key words
Aurora kinase,Cyanopyridine,Aminopyrazole
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined