Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists.
Bioorganic & Medicinal Chemistry Letters(2009)
Abstract
A novel series of 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists were identified.
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Key words
3,4-Dioxocyclobut-1-enyl-hydrazine,Antagonists,CXCR2,Chemokine receptor
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