Malignant peripheral nerve sheath tumours of the infraorbital nerve: case report and literature review.

Objective: We report a case of malignant peripheral nerve sheath tumour seen in our department. Method: We present case reports and a review of the world literature concerning malignant peripheral nerve sheath tumour. Results: A 38-year-old Caucasian woman was diagnosed with malignant peripheral nerve sheath tumour of the infraorbital nerve. She underwent a wide enbloc resection followed by a course of radiotherapy. A five-year post-operative magnetic resonance imaging scan revealed no evidence of recurrence. Conclusion: Malignant peripheral nerve sheath tumours are rare in the head and neck. An awareness of their occurrence is important for early diagnosis. Management involves: accurate histological diagnosis; radiological imaging to define tumour extent and plan resection. wide surgical excision with histologically negative margins reconstruction of the tissue defect, and post-operative radiotherapy.