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The role of intracellular Ca2+ in apoptosis induced by hyperthermia and its enhancement by verapamil in U937 cells

Keisuke Kameda,Takashi Kondo,Kiyoshi Tanabe,Qing-Li Zhao,Hikaru Seto

International Journal of Radiation Oncology*Biology*Physics（2001）

Cited 54|Views5
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Abstract
Purpose: The relationship between apoptosis induced by 42°C and 44°C hyperthermia alone or in combination with verapamil and changes in intracellular Ca2+ concentration ([Ca2+]i) was investigated in U937 cells.
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Key words
Apoptosis,Hyperthermia,Verapamil,Cytosolic Ca2+,BAPTA-AM
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