Synthesis of new 2 H -benzimidazole 1,3-dioxide derivatives analogous to separase inhibitor (Sepin-1)

E. A. Chugunova,N. I. Akylbekov, M. R. Gaziev,V. A. Samsonov,A. B. Dobrynin,A. R. Burilov

Russian Journal of Organic Chemistry（2018）

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摘要

New biologically active 2 H -benzimidazole 1,3-dioxide derivatives, analogs of Sepin-1, have been synthesized starting from benzofuroxan. Electrophilic substitution of hydrogen in the 2 H -benzimidazole ring occurs at different positions, depending on the electrophile nature.

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