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左卡尼汀对少弱精子离心过程中的保护作用

Medical Journal of Qilu(2011)

Cited 23|Views6
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Abstract
目的探讨左卡尼汀对精子体外离心过程中功能的保护作用。方法按WHO标准选取30份少弱精子样本,每份样本各取450μL,分为对照组和实验组,对照组仅加入EBSS平衡液,实验组加入含有一定水平左卡尼汀的EBSS平衡液,两组均1 200 r/min离心10 min后吸管吹打混匀,检测两组丙二醛及活性氧水平。结果实验组与对照组相比丙二醛及活性氧水平明显降低,差异有显著性(t=2.342、2.219,P<0.05)。结论左卡尼汀对少弱精子体外离心过程中所受氧化应激损伤具有明显保护作用。
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Key words
centrifugation,cytoprotection,asthenozoospermia,L-carnitine
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