Synthesis and study of a molecularly imprinted polymer for the specific extraction of indole alkaloids from Catharanthus roseus extracts.

C Lopez, B Claude,Ph Morin,J-P Max,R Pena, J-P Ribet

Analytica Chimica Acta（2011）

Cited 49|Views1

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Abstract

Two molecularly imprinted polymers (MIP) for catharanthine and vindoline have been synthesized in order to specifically extract these natural indole alkaloids from Catharanthus roseus by solid-phase extraction (SPE). Each MIP was prepared by thermal polymerisation using catharanthine (or vindoline) as template, methacrylic acid (or itaconic acid) as functional monomer, ethylene glycol dimethacrylate (EDMA) as cross-linking agent and acetonitrile (or acetone) as porogenic solvent.

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Key words

Molecularly imprinted polymer,Indole alkaloids,Catharanthus roseus,Catharanthine,Vindoline,Solid-phase extraction,Plant extract,Imprinting factor

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