Content changes and significance of of serum mitochondrial coupling factor-6 in patients with coronary heart disease complicating chronic heart failure

Objective To discuss the content changes and significance of serum mitochondrial coupling factor-6(CF6) in patients with coronary heart disease(CHD) complicating chronic heart failure(CHF).Methods The CHD patients(n=83) diagnosed by coronary angiography(CAG) were chosen,among them 53 with complication of CHF were further divided into subgroups of grade Ⅱ,grade Ⅲ and grade Ⅳ according to the heart function grade of NYHA.The patients(n=30) with normal heart function were chosen as control group.Results Compared with control group,the content of serum CF6 and brain natriuretic peptide(BNP) were higher and increased as the aggravation of CHF(P0.01).Conclusion The content of CF6 and BNP are related to the degree of CHF.