Effects of melatonin on the proliferation and cis-diamminedichloroplatinum (CDDP) sensitivity of cultured human ovarian cancer cells.

M Futagami,S Sato,T Sakamoto,Y Yokoyama,Y Saito

Gynecologic Oncology（2001）

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摘要

Objectives. In this study, we investigated the antiproliferative effect and telomerase activity of melatonin with or without cis-diamminedichloroplatinum (CDDP) on CDDP-sensitive HTOA cells and CDDP-resistant OVCAR-3 cells of cultured human ovarian cancer.

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melatonin,cis-diamminedichloroplatinum,alamarBlue assay,telomerase activity,fluorescence-based telomeric repeat amplification protocol

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