T-bet, pSTAT1 and pSTAT3 expression in peripheral blood mononuclear cells during pregnancy correlates with post-partum activation of multiple sclerosis.
Clinical Immunology（2009）
Abstract
In pregnant women affected by multiple sclerosis (MS) we observed increased percentages of CD4+CD25+Foxp3+ T regulatory cells at the 1st and the 2nd trimester of gestation that was associated with a decreased T-bet expression in CD4+ T cells.
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Key words
Multiple sclerosis,Pregnancy,Transcription factors,pSTAT1,pSTAT3,T-bet,Foxp3,T regulatory cells
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