Long-term safety and tolerability of tapentadol extended release for the management of chronic low back pain or osteoarthritis pain.

PAIN PRACTICE(2010)

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摘要
Tapentadol ER (100 to 250 mg bid) was associated with better gastrointestinal tolerability than oxycodone HCl CR (20 to 50 mg bid) and provided sustainable relief of moderate to severe chronic knee or hip osteoarthritis or low back pain for up to 1 year.
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关键词
analgesics,opioid,low back pain
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