狼疮性肾炎中ANCN及其靶抗原的临床研究
JOURNAL OF SHANDONG MEDICAL COLLEGE(2006)
Abstract
目的 探讨狼疮性肾炎(LN)患者血清中抗中性粒细胞胞浆抗体(ANCN)及其靶抗原的表达及临床意义.方法 收集103例LN病人血清,分别用间接免疫荧光法(IIF)及免疫酶联吸附实验(ELISA)法检测ANCA的阳性率及其靶抗原的表达率.结果 活动期LN的ANCA阳性率及靶抗原的表达率均高于稳定期LN,且以组蛋白酶G (CG)及乳铁蛋白(LF)为主,活动期LN中抗dsDNA、低补体血症、血沉增快及肾功能下降的发生率均明显高于稳定期.结论 LN患者血清中ANCN阳性及靶抗原的表达与LN的活动有关,肾脏损害以ANCA阳性者为重.
MoreTranslated text
Key words
Antibody Engineering
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined