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肺癌患者外周血CD4~+CD25~+FOXP3~+调节性T细胞的表达及临床意义

Li Shirong,Xue Feng,Wang Yunzeng

Medical Laboratory Science and Clinics（2007）

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Abstract
目的通过研究肺癌患者外周血中CD4+CD25+FOXP3+调节性T淋巴细胞的变化,探讨肺癌的发病机制。方法用荧光标记的单克隆抗体染色外周血单个核细胞,利用流式细胞仪检测CD4+CD25+FOXP3+调节性T淋巴细胞的改变。结果肺癌患者外周血CD4+CD25+FOXP3+调节性T淋巴细胞显著增多。结论CD4+CD25+FOXP3+调节性T淋巴细胞的增多与机体的免疫力下降以及肿瘤的发生发展有一定关系。
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Key words
CD4+CD25+,FOXP3,Lung cancer
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