参附注射液对老年人手术后早期康复的影响
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine(2008)
Abstract
目的:观察参附注射液对老年患者手术后早期康复的影响,并探讨其可能的机制.方法:100例随机分为对照组和参附注射液(参附组),每组50例.参附组于手术前3天起至术后3天,每天用参附注射液100ml静脉滴注;对照组行常规治疗.术后每天观察并记录肠蠕动恢复时间、肛门排气时间、切口愈合情况,并作C-反应蛋白、皮质醇浓度、部分细胞因子及SOD、MDA的检测.结果:参附组与对照组比较,术后疲劳指数、C-反应蛋白、皮质醇浓度、TNF-α、MDA明显下降(P<0.01或P<0.05),IL-2、SOD水平显著提高(P<0.01).结论:参附注射液能降低手术后应激反应,减少炎症因子的表达,减轻组织损伤,在一定程度上促进老年患者手术后的早期康复.
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Key words
shenfu injection after operation response to a stimulus TNF-α SOD
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