Constipation and cardiovascular disease: A two-sample Mendelian randomization analysis.

Qichao Dong,Delong Chen,Yuxuan Zhang, Yi Xu,Longhui Yan,Jun Jiang

Frontiers in cardiovascular medicine（2023）

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摘要

This MR study demonstrated suggestive causal associations of constipation on AF, despite no associations achieving a significance value after multiple testing corrections. There was no evidence of an association between constipation and the risk of CAD, MI, HF, stroke, or stroke subtypes.

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关键词

Mendelian randomization,atrial fibrillation,cardiovascular disease,causality,constipation

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