The Efficacy of 'radio Guided Occult Lesion Localization' (ROLL) Versus 'Wire-Guided Localization' (WGL) in Breast Conserving Surgery for Non-Palpable Breast Cancer: A Randomized Clinical Trial – ROLL Study

With the increasing number of non palpable breast carcinomas, the need of a good and reliable localization method increases. Currently the wire guided localization (WGL) is the standard of care in most countries. Radio guided occult lesion localization (ROLL) is a new technique that may improve the oncological outcome, cost effectiveness, patient comfort and cosmetic outcome. However, the studies published hitherto are of poor quality providing less than convincing evidence to change the current standard of care.