Clofibrate-induced myopathy in the rat.
Acta neuropathologica（1978）
摘要
Rats were given daily injections of 0.2 or 0.5 g/kg chlorophenoxyisobutyrate (clofibrate) for 9 to 46 days. Lower leg muscles were studied with light and electron microscopy. Daily treatment with 0.5 g/kg of the drug for 26--46 days caused myopathic changes.
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关键词
experimental animal,histo- chemistry,clofibrate,striated muscle,electron microscopy
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