Myxoma of the oral soft tissues: Report of a case and literature review.

Soft tissue myxomas are benign tumors of uncertain differentiation, 1 Kempson R. Fletcher C. Evans H. et al. Tumors of soft tissues. in: Atlas of Tumor Pathology (ser 3, fasc 30). Armed Forces Institute of Pathology, Washington DC1998: 419 Google Scholar arising in somatic soft tissues mostly within skeletal muscles, dermal and subcutaneous tissues, pelviperineal tissues, and adjacent to a large joint. 2 Miettinen M. Hockerstedt K. Reitamo J. et al. Intramuscular myxoma A clinicopathological study of twenty three cases. Am J Clin Pathol. 1985; 84: 265 Crossref PubMed Scopus (78) Google Scholar , 3 Meis J. Enzinger F.M. Juxta-articular myxoma A clinical and pathologic study of 65 cases. Hum Pathol. 1992; 23: 639 Abstract Full Text PDF PubMed Scopus (66) Google Scholar , 4 Hill T.L. Jones B.E. Park K.H. Myxoma of the skin of the finger. J Am Acad Dermatol. 1990; 22: 343 Abstract Full Text PDF PubMed Scopus (16) Google Scholar , 5 Begin L.R. Clement P.B. Kirk M.E. et al. Aggressive angiomyoma of pelvic soft part: A clinicopathologic study of nine cases. Hum Pathol. 1985; 16: 621 Abstract Full Text PDF PubMed Scopus (210) Google Scholar , 6 Fetch J.F. Laskin W.B. Lefkowitz M. et al. Aggressive angiomyxoma A clinicopathologic study of 29 female patients. Cancer. 1996; 78: 79 Crossref PubMed Scopus (288) Google Scholar , 7 Allen P.W. Dymock R.B. MacCormac W.B. Superficial angiomyxomas with or without epithelial components Report of 30 tumors in 28 patients. Am J Surg Pathol. 1988; 12: 519 Crossref PubMed Scopus (190) Google Scholar , 8 Ferreiro J.A. Carney J.A. Myxomas of the external ear and their significance. Am J Surg Pathol. 1994; 18: 274 Crossref PubMed Scopus (62) Google Scholar They are classified as intramuscular myxoma, digital myxoma, superficial angiomyxoma, aggressive angiomyxoma, and juxta-articular myxoma. 1 Kempson R. Fletcher C. Evans H. et al. Tumors of soft tissues. in: Atlas of Tumor Pathology (ser 3, fasc 30). Armed Forces Institute of Pathology, Washington DC1998: 419 Google Scholar Although they are not encapsulated and may progressively invade the surrounding tissues, they have a benign behavior. Soft tissue myxomas affect persons of all ages although rarely children and young adolescents. 9 Batsakis J.G. Tumors of the Head and Neck: Clinical and Pathological Considerations. ed 2. Williams & Wilkins, Baltimore1979: 359 Google Scholar Twenty percent of tumors grow intramuscularly (intramuscular myxoma); they are found frequently in the muscles of the thigh. 2 Miettinen M. Hockerstedt K. Reitamo J. et al. Intramuscular myxoma A clinicopathological study of twenty three cases. Am J Clin Pathol. 1985; 84: 265 Crossref PubMed Scopus (78) Google Scholar , 10 Nielsen G.P. O’Connell J.X. Rosenberg A.E. Intramuscular myxoma: A clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants. Am J Surg Pathol. 1998; 22: 1222 Crossref PubMed Scopus (96) Google Scholar In the maxillofacial regions soft tissue myxomas have been found in the skin and subcutaneous tissue, the fascia, the parotid gland, the larynx, the tonsils, and the ear. 11 Batsakis J.G. Myxomas of soft tissues and the facial skeleton. Ann Otol Rhinol Laryngol. 1987; 96: 618 PubMed Google Scholar