洛索洛芬钠片治疗膝关节骨性关节炎60例临床研究
Journal of Shanxi College of Traditional Chinese Medicine(2013)
Abstract
目的:评价洛索洛芬钠片治疗膝关节骨性关节炎的疗效和安全性。方法:选取膝关节骨性关节炎患者120例,随机分为2组,每组60例。治疗组口服洛索洛芬钠片治疗,对照组口服布洛芬缓释胶囊治疗,疗程均为4 w。结果:治疗组自身健康状况主观感受、生理领域、心理领域得分高于对照组(P<0.05);治疗后2组Lysholm临床疗效评分均显著提高,但治疗组评分明显高于对照组(P<0.05);治疗组不良反应发生率低于对照组(P<0.05)。结论:洛索洛芬钠能够明显提高膝关节骨性关节炎患者生存质量,改善症状和功能,安全性好。
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