In Situ Implantation Preserves Myogenic and Neuronal Characteristics of Intrinsically Innervated Bioengineered Human Internal Anal Sphincter (IAS)

younger on average (65.5 ±10.7) than bleeding cases (70.0±11.4;p = 0.056).Conclusions: 1.The rate of gastrointestinal bleeding among patients on dual antiplatelet therapy after PCI with PPI co-therapy is 1.8 cases per 100 patient-years.2. Most bleeding events occur during the first year of follow-up and are located in the lower GI tract.3. Risk factors predictive of a bleeding event are co-therapy with warfarin, age and a peptic ulcer history.