2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases
Bioorganic & Medicinal Chemistry Letters(2007)
Abstract
A potent series of broad-spectrum antivirals against human herpesviruses has been identified which inhibit HCMV, HSV-1, EBV, and VZV polymerases.
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Key words
Cytomegalovirus,HCMV,Varicella-zoster,VZV,HSV
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