Synthesis of α and β anomers of UDP-N-acetylmuramic acid
Carbohydrate Research(1994)
摘要
A convenient synthesis of UDP-N-acetylmuramic acid, a key compound for the study of the cytoplasmic synthetases of bacterial peptidoglycan, is described. Separation of its two anomers was carried out by HPLC. The α anomer is identical with natural UDP-N-acetylmuramic acid. Both anomers are substrates for the l-alanine-adding enzyme from Escherichia coli with Km values of 0.13 mM (α) and 2 mM (β).
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关键词
synthesis,udp-n-acetylmuramic
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