DCRRT治疗重症急性胰腺炎并急性肺损伤的临床观察

Shandong Medical Journal(2011)

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Abstract
目的 探讨日间连续性肾替代疗法( DCRRT)治疗重症急性胰腺炎(SAP)并急性肺损伤(AU)的临床疗效.方法 将40例SAP并ALI患者随机分为DCRRT组、对照组各20例,检测两组治疗前后血浆TNF-α、IL-6、IL-8,比较其生命体征、氧合指数、急性生理与慢性健康评估评分(APACHEⅡ评分)、机械通气时间、ICU住院时间及病死率.结果 与对照组比较,DCRRT组TNF-α、IL-6、IL-8下降,生命体征好转,氧合指数提高,APACHEⅡ评分下降,机械通气及ICU住院时间缩短,病死率降低(P<0.01或<0.05).结论 DCRRT能促进SAP并ALI患者的肺功能恢复,减少机械通气时间,缩短ICU住院时间,降低病死率.
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Key words
daytime,continuous,lung injury,renal replacement therapy,pancreatitis,acute
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