Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NFκB signalling

Conclusion These findings provide evidence for the involvement of the nuclear hormone receptors PPARγ and VDR in butyrate-mediated inhibition of inducible NFκB activation dependent on the stimulated signalling pathway. Moreover, VDR appears to play an inhibitory role in the regulation of basal NFκB signalling.