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Hepatoprotective phytocompounds from Cryptomeria japonica are potent modulators of inflammatory mediators

Phytochemistry(2008)

Cited 49|Views24
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Abstract
This study demonstrated that phytocompounds from Cryptomeria japonica wood extracts possessed potent anti-inflammatory and hepatoprotective activities by attenuating proinflammatory mediator activities and CCl4- induced acute liver injury in mice. Three terpenoids (1–3) were found to be the major bioactive compounds which contributed to the observed bioactivities.
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Key words
Cryptomeria japonica,Taxodiaceae,Hepatoprotection,Cycloxygenase-2,Nitric oxide,Inducible nitric oxide synthase,Heme oxygenase-1,Terpenoids
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