Lung function in idiopathic pulmonary fibrosis - extended analyses of the IFIGENIA trial
Respiratory Research(2009)
摘要
The randomized placebo-controlled IFIGENIA-trial demonstrated that therapy with high-dose N-acetylcysteine (NAC) given for one year, added to prednisone and azathioprine, significantly ameliorates (i.e. slows down) disease progression in terms of vital capacity (VC) (+9%) and diffusing capacity (DLco) (+24%) in idiopathic pulmonary fibrosis (IPF). To better understand the clinical implications of these findings we performed additional, explorative analyses of the IFGENIA data set.
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关键词
Idiopathic Pulmonary Fibrosis,Vital Capacity,Usual Interstitial Pneumonia,Idiopathic Pulmonary Fibrosis Patient,Idiopathic Interstitial Pneumonia
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