18F-FDG SPECT显像区别阿尔茨海默病和血管性痴呆的临床研究
Stroke and Nervous Diseases（2008）
Abstract
目的 探讨阿尔茨海默病(AD)与血管性痴呆(VD)18F-脱氧葡萄糖(18F-FDG)单光子发射计算机断层(SPECT)的影像特点.方法 静脉注射18F-FDG 45 min后行脑断层显像,获得脑显像特征,并加以分析、比较.结果 22例AD患者可见双侧颞、顶、额叶对称或单侧优势半球的颞、顶、额叶异常代谢灶.20例VD患者除皮质各叶显示异常代谢灶外,合并基底节、丘脑、枕叶异常代谢灶,与基础病变(头颅CT或MRI定位)一致.结论 18F-FDG SPECF可作为鉴别诊断AD、VD的有效手段.
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Key words
Deoxyglucose Positron emission on tomography Alzheimer's disease Vascular dementia
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