Discovery of 4-Azaindoles As Novel Inhibitors of C-Met Kinase.
Bioorganic & Medicinal Chemistry Letters(2009)
Abstract
A series of 4-azaindole inhibitors of c-Met kinase is described. The postulated binding mode was confirmed by an X-ray crystal structure and series optimisation was performed on the basis of this structure. Future directions for series development are discussed.
MoreTranslated text
Key words
c-Met Kinase inhibitor,Hepatocyte growth factor receptor inhibitor,Kinase inhibitor,Azaindole
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined