A wireless bio-MEMS sensor for C-reactive protein detection based on nanomechanics.

Chun-Hao Chen,Rong-Zhang Hwang,Long-Sun Huang,Shi-Ming Lin,Hsiao-Chin Chen,Yu-Che Yang,Yu-Tso Lin,Shih-An Yu,Yo-Sheng Lin,Yiao-Hong Wang,Nai-Kuan Chou,Shey-Shi Lu

IEEE Transactions on Biomedical Engineering（2009）

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摘要

A quick wireless label-free detection of disease-related C-reactive proteins (CRPs) using a 200-mum-long microelectromechanical systems (MEMS) microcantilever housed in a 7times7 mm2 reaction chamber with a safe reusable feature is reported. The assay time ranges from about 30 min to 3 h, depending on accuracy. The deflection of the microcantilever due to specific CRP-antiCRP binding is detected u...

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关键词

Wireless sensor networks,Biosensors,Proteins,Position sensitive particle detectors,Microelectromechanical systems,Micromechanical devices,Amplitude shift keying,Transceivers,CMOS integrated circuits,CMOS process

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