猪静脉空气栓塞模型的经食管超声心动图实验研究
Chinese Journal of Medical Ultrasound(Electronic Version)(2006)
Abstract
目的观察空气栓子在猪右心腔内的超声声像图变化及猪静脉空气栓塞的致死量。方法经6头健康梅白猪的颈内静脉依次注入0.05~4ml/kg空气,经食管超声心动图连续观察猪右心腔内声像图变化,并记录静脉空气栓塞的致死量。结果随着注入的空气量增加,右心腔内游动的点状强回声逐渐增多,甚至充满整个心腔,然后逐渐分散消失,排空时间为15s~40min,其中1头实验猪发生反常栓塞。猪静脉空气栓塞的累积致死量为276~667ml。结论经食管超声心动图能敏感检测猪右心腔中空气栓子的超声表现,健康梅白猪静脉空气栓塞的平均累积致死量为(397±105)ml。
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Key words
Laboratory animals,Air embolism,Transesophageal echocardiography
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