瑞格列奈联合二甲双胍对2型糖尿病的疗效观察
Journal of Gannan Medical University(2010)
Abstract
目的:观察瑞格列奈和二甲双胍联合治疗2型糖尿病的疗效.方法:将107例2型糖尿病患者在饮食控制和运动锻炼基础治疗上随机分成对照组,观察组.对照组52例,予格列吡嗪联合二甲双胍治疗;观察组55例,予瑞格列奈联合二甲双胍治疗.观察两组患者治疗前、治疗12周后空腹血糖、餐后2h血糖、糖化血红蛋白的变化.结果:两组患者空腹血糖、餐后2h血糖、糖化血红蛋白治疗后均有改善,其中观察组与对照组疗效比较上述指标改善更为明显,差异有显著性(P<0.05).结论:瑞格列奈联合二甲双胍比格列吡嗪联合二甲双胍对2型糖尿病患者空腹血糖、餐后2h血糖及糖化血红蛋白的疗效更显著.
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Key words
metformin,type 2 diabetes,Repaglinide
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