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Effect of methotrexate and folinic acid on accumulation of iron in mice

M.P Iqbal,N Mehboobali,F Sultana,F.B Khan,I.A Burney,G.N Kakepoto

Medical Hypotheses（2003）

Cited 2|Views8
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Abstract
A mouse-model was used to investigate the effect of methotrexate (MTX) and folinic acid on accumulation of iron in young growing mice. Four equal groups of Balb/c young male mice were treated (subcutaneously) with either MTX, or folinic acid, or MTX plus folinic acid, or physiological saline on every second day.
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iron
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