Triazole Antifungals .5. Synthesis And Antifungal Activities Of Some Amides Related To 3-Acylamino-2-Aryl-1-Triazolyl-2-Butanol

T Tanaka,N Takeda,T Konosu,H Yasuda,S Oida

Cheminform（1992）

引用 9|浏览1

暂无评分

摘要

Amides, 2 and 3, related to the potent antifungal triazole-amide 3-acylamino-2-aryl-1-triazolyl-2-butanol (1) were synthesized starting from the triazole-alcohol 6. The antifungal activity of 2 and 3 against a mouse systemic Candida albicans infection was found to be less potent than that of 1.

查看译文

关键词

ANTIFUNGAL ACTIVITY, 1,2,4-TRIAZOLE, 3-CARBAMOYL-2-ARYL-1-(TRIAZOL-1-YL)-2-BUTANOL, 4-ACYLAMINO-2-ARYL-3-METHYL-1-(TRIAZOL-1-YL)-2-BUTANOL, STRUCTURE-ACTIVITY RELATIONSHIP, BETA-LACTONE, STEREOCHEMISTRY ASSIGNMENT

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要